Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586043 | 0.85 | CXCR2 (0.56) | CXCR2TGFBR1 | |
| Trifluoroacetic Acid SCHEMBL4587172 | 0.83 | CXCR2 (0.64) | CXCR2 | |
| SCHEMBL6563484 | 0.80 | STS (0.51) | TGFBR1 | |
| SCHEMBL6565706 | 0.78 | TGFBR1 (0.51) | TGFBR1 | |
| SCHEMBL6564860 | 0.78 | CXCR2 (0.72) | CXCR2 | |
| Trifluoroacetic Acid SCHEMBL7548881 | 0.78 | CXCR2 (0.49) | CXCR2 | |
| SCHEMBL4587255 | 0.77 | TGFBR1 (0.52) | CXCR2TGFBR1 | |
| SCHEMBL4587779 | 0.73 | CXCR2 (0.64) | CXCR2 | |
| SCHEMBL5438708 | 0.72 | CXCR2 (0.72) | CXCR2 | |
| SCHEMBL6566637 | 0.72 | CXCR2 (0.58) | CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161232-A4 | HYDROXY DIPHENYL UREA SULFONAMIDES AS IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-09-18 | — | — | EP | disclosed |
| EP-1161232-A1 | HYDROXY DIPHENYL UREA SULFONAMIDES AS IL-8 RECEPTOR ANTAGONISTS | SmithKline Beecham Corporation (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000035442-A1 | HYDROXY DIPHENYL UREA SULFONAMIDES AS IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-06-22 | — | — | WO | disclosed |