Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7503953 | 0.96 | EDNRA (0.53) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7506376 | 0.93 | EDNRA (0.51) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7494119 | 0.87 | EDNRA (0.60) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8043446 | 0.84 | EDNRA (0.59) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7499196 | 0.83 | EDNRA (0.45) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7496869 | 0.83 | EDNRA (0.66) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7501806 | 0.83 | EDNRA (0.57) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7506638 | 0.81 | EDNRA (0.45) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8046639 | 0.80 | EDNRA (0.65) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7496900 | 0.80 | EDNRA (0.64) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776325-B1 | NOVEL USE AND NOVEL DERIVATIVES OF IMIDAZOLE, METHOD FOR PREPARING SAME, NOVEL INTERMEDIATES THUS OBTAINED, MEDICINAL APPLICATIONS OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2002-11-20 | — | — | EP | claimed |