Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | BRS3 | P32247 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7496916 | 0.90 | EDNRA (0.54) | EDNRABRS3EDNRBAGTR1AGTR2 | |
| SCHEMBL7506638 | 0.89 | EDNRA (0.45) | EDNRATLR7BRS3KDM4EALDH1A1 | |
| SCHEMBL7501556 | 0.87 | SMN1; SMN2 (0.43) | EDNRABRS3KDM4EALDH1A1HPGD | |
| SCHEMBL8435078 | 0.85 | EDNRA (0.47) | EDNRABRS3SMN1; SMN2AGTR1AGTR2 | |
| SCHEMBL7499419 | 0.84 | EDNRA (0.45) | EDNRABRS3KDM4EALDH1A1HPGD | |
| SCHEMBL6580281 | 0.84 | KDM4E (0.39) | EDNRABRS3KDM4EALDH1A1HPGD | |
| SCHEMBL7501892 | 0.83 | EDNRA (0.48) | EDNRATLR7KDM4EALDH1A1HPGD | |
| SCHEMBL7501757 | 0.81 | EDNRA (0.55) | EDNRABRS3EDNRB | |
| SCHEMBL8432538 | 0.81 | EDNRA (0.40) | EDNRABRS3AGTR1AGTR2LMNA | |
| SCHEMBL7501806 | 0.79 | EDNRA (0.57) | EDNRATLR7KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776325-B1 | NOVEL USE AND NOVEL DERIVATIVES OF IMIDAZOLE, METHOD FOR PREPARING SAME, NOVEL INTERMEDIATES THUS OBTAINED, MEDICINAL APPLICATIONS OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2002-11-20 | — | — | EP | claimed |