Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.75 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.75 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.75 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.75 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.75 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.75 |
| ▸ | SCN1A | P35498 | 1/20 | 0.75 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.75 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.75 |
| ▸ | HTR1A | P08908 | 2/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.68 |
| ▸ | DRD2 | P14416 | 5/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11854599 | 0.90 | ADRA2A (0.84) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL14454754 | 0.87 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Piperoxan SCHEMBL29404377 | 0.86 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Piperoxan SCHEMBL83631 | 0.86 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Piperoxan SCHEMBL31464193 | 0.86 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Piperoxan SCHEMBL12503311 | 0.84 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Piperoxan SCHEMBL9869634 | 0.84 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL20438314 | 0.83 | ADRA2A (0.73) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL20438315 | 0.83 | ADRA2A (0.73) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL4139299 | 0.83 | ADRA2A (0.73) | ADRA2AADRA2BADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-B1 | ANTIMICROBIAL AGENTS | RANBAXY LAB LTD (IN) | 2013-01-02 | — | — | EP | disclosed |
| EP-0966437-B1 | 5-AROYLNAPHTHALENE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2002-06-12 | — | — | EP | disclosed |