Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 2/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 2/20 | 1.00 |
| ▸ | ADRA1D | P25100 | 2/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 2/20 | 1.00 |
| ▸ | ADRA1B | P35368 | 2/20 | 1.00 |
| ▸ | SCN1A | P35498 | 1/20 | 1.00 |
| ▸ | SCN2A | Q99250 | 1/20 | 1.00 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 1.00 |
| ▸ | HTR1A | P08908 | 2/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.69 |
| ▸ | DRD2 | P14416 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperoxan SCHEMBL31464193 | 1.00 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Piperoxan SCHEMBL29404377 | 1.00 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Piperoxan SCHEMBL9869634 | 0.98 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Piperoxan SCHEMBL12503311 | 0.98 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL14454754 | 0.98 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Piperoxan SCHEMBL7088293 | 0.95 | ADRA2A (0.91) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL11854599 | 0.92 | ADRA2A (0.84) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Piperoxan SCHEMBL15864191 | 0.92 | ADRA2A (0.84) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL7501915 | 0.86 | ADRA2A (0.75) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL2546786 | 0.86 | ADRA2A (0.74) | ADRA2AADRA2BADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6468 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362369-B1 | — | — | None | — | — | US | claimed |
| US-20260108493-A1 | COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND | CAAMTECH, INC. (US) | 2026-04-23 | — | — | US | claimed |
| US-12590100-B2 | Tetrahydro-spiroindoline-pyrrolopyrrole-triones inhibitors of the NRF2-β-TrCP interaction for use in the treatment of fatty liver disease | UNIV MADRID AUTONOMA (ES) | 2026-03-31 | — | — | US | claimed |
| US-20260069599-A1 | INHIBITORS OF BROMODOMAIN-CONTAINING PROTEIN 4 AND PHOSPHOINOSITIDE 3-KINASE | UNIV NEBRASKA (US) | 2026-03-12 | — | — | US | claimed |
| US-20250186415-A1 | EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS | FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT | 2025-06-12 | — | — | US | claimed |
| WO-2025111482-A1 | COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS | BEXSON BIOMEDICAL, INC. (US) | 2025-05-30 | — | — | WO | claimed |
| EP-4489858-A1 | EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS | Harrow IP, LLC (US) | 2025-01-15 | — | — | EP | claimed |
| WO-2024251133-A1 | HETEROCYCLIC COMPOUND AS α5-GABAA RECEPTOR MODULATOR AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2024-12-12 | — | — | WO | claimed |
| EP-4277620-B1 | TETRAHYDRO-SPIROINDOLINE-PYRROLOPYRROLE-TRIONES INHIBITORS OF THE NRF2-BETA-TRCP INTERACTION FOR USE IN THE TREATMENT OF FATTY LIVER DISEASE | UNIV MADRID AUTONOMA (ES) | 2024-12-04 | — | — | EP | claimed |
| CN-119039135-A | Carboxyl chalcone derivative and preparation method and application thereof | 四川大学 | 2024-11-29 | — | — | CN | claimed |
| EP-0105361-A1 | ANTAGONISM OF CENTRAL NERVOUS SYSTEM DRUGS BY THE ADMINISTRATION OF 4-AMINOPYRIDINE ALONE OR IN COMBINATION WITH OTHER DRUGS | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1984-04-18 | — | — | EP | claimed |
| EP-0042556-B1 | PROCESS FOR THE MANUFACTURE OF ALKYLHYDRAZONE CATIONIC DYES AND THEIR DYESTUFF BASES | BAYER AG (DE) | 1984-02-08 | — | — | EP | claimed |
| EP-0095666-A2 | Tetrahydro-benzo(e) isoindolines | ABBOTT LABORATORIES (US) | 1983-12-07 | — | — | EP | claimed |
| WO-1983003541-A1 | ANTAGONISM OF CENTRAL NERVOUS SYSTEM DRUGS BY THE ADMINISTRATION OF 4-AMINOPYRIDINE ALONE OR IN COMBINATION WITH OTHER DRUGS | UNIV GEORGIA RES FOUND (US) | 1983-10-27 | — | — | WO | claimed |
| US-4376728-A | Process for the preparation of cationic alkylarylhydrazone dyestuffs and color bases thereof | BAYER AKTIENGESELLSCHAFT (DE) | 1983-03-15 | — | — | US | claimed |
| US-4310524-A | TCA Composition and method for rapid onset antidepressant therapy | RICHARDSON-MERRELL, INC. (US) | 1982-01-12 | — | — | US | claimed |
| EP-0004366-B1 | HAIR DYEING COMPOSITIONS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-07-08 | — | — | EP | claimed |
| US-4217305-A | HYPOTENSIVE AGENTS, ADRENERGIC BLOCKING AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1980-08-12 | — | — | US | claimed |
| US-3991198-A | PIPEROXAN | NELSON RESEARCH & DEVELOPMENT COMPANY (US) | 1976-11-09 | — | — | US | claimed |
| US-3967835-A | Pressure-sensitive copying material | HODOGAYA CHEMICAL CO., LTD. (JA) | 1976-07-06 | — | — | US | claimed |