Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 15/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7488941 | 0.89 | DRD4 (0.50) | DRD4DRD3MOGAT2 | |
| SCHEMBL7498335 | 0.88 | DRD4 (0.52) | DRD4DRD2 | |
| SCHEMBL7495139 | 0.87 | DRD4 (0.40) | DRD4DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL7497767 | 0.87 | DRD4 (0.52) | DRD4DRD2DRD3ALDH1A1 | |
| SCHEMBL7497797 | 0.85 | DRD4 (0.46) | DRD4DRD2DRD3 | |
| SCHEMBL7502764 | 0.85 | DRD4 (0.50) | DRD4DRD2 | |
| SCHEMBL7498678 | 0.85 | DRD4 (0.57) | DRD4DRD2DRD3 | |
| SCHEMBL8330452 | 0.81 | ALDH1A1 (0.43) | MCHR1BCHEACHEBACE1KDM4E | |
| SCHEMBL7495891 | 0.79 | DRD4 (0.50) | DRD4DRD3MOGAT2BCHEACHE | |
| SCHEMBL8616978 | 0.78 | DRD4 (0.52) | DRD4MCHR1HIF1AEPAS1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760362-B1 | DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN SEIFUN GROUP INC (JP) | 2002-08-14 | — | — | EP | disclosed |
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |