Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 20/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7502764 | 0.91 | DRD4 (0.50) | DRD4DRD2 | |
| SCHEMBL7488941 | 0.91 | DRD4 (0.50) | DRD4CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7497767 | 0.90 | DRD4 (0.52) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7497797 | 0.89 | DRD4 (0.46) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7498678 | 0.89 | DRD4 (0.57) | DRD4DRD2 | |
| SCHEMBL7495139 | 0.88 | DRD4 (0.40) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7501988 | 0.88 | DRD4 (0.50) | DRD4DRD2 | |
| SCHEMBL7495891 | 0.80 | DRD4 (0.50) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7493202 | 0.80 | DRD4 (0.47) | DRD4CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8326148 | 0.80 | LTA4H (0.45) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760362-B1 | DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN SEIFUN GROUP INC (JP) | 2002-08-14 | — | — | EP | disclosed |
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |