Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9178606 | 0.97 | OPRM1 (0.50) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL22982430 | 0.97 | OPRM1 (0.50) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL28161558 | 0.97 | OPRM1 (0.50) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL13858888 | 0.94 | OPRM1 (0.58) | OPRM1CA1SPHK1LMNATSHR | |
| SCHEMBL6531560 | 0.90 | DNM1 (0.43) | OPRM1CA1LMNATSHRTHRB | |
| SCHEMBL13858988 | 0.90 | OPRM1 (0.55) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL31169240 | 0.90 | OPRM1 (0.55) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL10657571 | 0.90 | OPRM1 (0.55) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL11480610 | 0.90 | OPRM1 (0.55) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL325629 | 0.90 | OPRM1 (0.55) | OPRM1SPHK1LMNATSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968342-A1 | COMPOSITIONS COMPRISING THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF | The Regents Of The University Of Michigan (US) | 2016-01-20 | — | — | EP | claimed |
| CN-105188705-A | Compositions comprising thienopyrimidine and thienopyridine compounds and methods of use thereof | UNIV MICHIGAN | 2015-12-23 | — | — | CN | claimed |
| WO-2014164543-A1 | COMPOSITIONS COMPRISING THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-10-09 | — | — | WO | claimed |
| US-20200171214-A1 | BIORESORBABLE SURFACE COATING FOR DELAYING DEGRADATION | DREI LILIEN PVG GMBH & CO. KG (DE) | 2020-06-04 | — | — | US | disclosed |
| EP-3648806-A1 | BIORESORBABLE SURFACE COATING FOR DELAYING DEGRADATION | Drei Lilien PVG GmbH & Co. KG (DE) | 2020-05-13 | — | — | EP | disclosed |
| WO-2019008192-A1 | BIORESORBABLE SURFACE COATING FOR DELAYING DEGRADATION | DREI LILIEN PVG GMBH & CO. KG (DE) | 2019-01-10 | — | — | WO | disclosed |
| US-10160769-B2 | Compositions comprising thienopyrimidine and thienopyridine compounds and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-12-25 | — | — | US | disclosed |
| EP-2968342-B1 | COMPOSITIONS COMPRISING THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF | UNIV MICHIGAN REGENTS (US) | 2018-10-03 | — | — | EP | disclosed |
| US-20170253611-A1 | COMPOSITIONS COMPRISING THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF | THE LEUKEMIA & LYMPHOMA SOCIETY, INC. | 2017-09-07 | — | — | US | disclosed |
| US-9505781-B2 | Compositions comprising thienopyrimidine and thienopyridine compounds and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-11-29 | — | — | US | disclosed |
| WO-2016040330-A1 | THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-03-17 | — | — | WO | disclosed |
| CN-105188705-A | Compositions comprising thienopyrimidine and thienopyridine compounds and methods of use thereof | UNIV MICHIGAN | 2015-12-23 | — | — | CN | disclosed |
| US-9216993-B2 | Compositions comprising thienopyrimidine and thienopyridine compounds and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2015-12-22 | — | — | US | disclosed |
| WO-2014164543-A1 | COMPOSITIONS COMPRISING THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-10-09 | — | — | WO | disclosed |
| EP-2430133-A1 | LUBRICATING COMPOSITION CONTAINING A MALIC ACID DERIVATIVE | The Lubrizol Corporation (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2011149810-A1 | LUBRICATING COMPOSITION | THE LUBRIZOL CORPORATION (US) | 2011-12-01 | — | — | WO | disclosed |
| EP-2367917-A1 | LUBRICATING COMPOSITION CONTAINING A COMPOUND DERIVED FROM A HYDROXY-CARBOXYLIC ACID | The Lubrizol Corporation (US) | 2011-09-28 | — | — | EP | disclosed |
| US-20110207635-A1 | Lubricating Composition Containing Metal Carboxylate | THE LUBRIZOL CORPORATION (US) | 2011-08-25 | — | — | US | disclosed |
| EP-2346967-A1 | LUBRICATING COMPOSITION CONTAINING METAL CARBOXYLATE | The Lubrizol Corporation (US) | 2011-07-27 | — | — | EP | disclosed |
| WO-2011034829-A1 | LUBRICATING COMPOSITION CONTAINING AN ESTER | THE LUBRIZOL CORPORATION (US) | 2011-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10160769-B2 | Compositions comprising thienopyrimidine and thienopyridine compounds and methods of use thereof | MLLT1, MLLT3, BMI1 | OPRM1 4679/4885CA1 3322/4885SPHK1 2575/4885 |
| US-20170253611-A1 | COMPOSITIONS COMPRISING THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF | MLLT1, MLLT3, BMI1 | OPRM1 4679/4885CA1 3322/4885SPHK1 2575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.