Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7500976 | 0.92 | ADRB2 (0.38) | HPGDKMT2AMEN1MAPTTHRB | |
| SCHEMBL7504090 | 0.89 | HPGD (0.39) | HPGDKMT2AMEN1MAPTTHRB | |
| SCHEMBL7499466 | 0.88 | ADRB2 (0.39) | HPGDKMT2AMEN1MAPTTHRB | |
| SCHEMBL7502023 | 0.84 | KCNH2 (0.37) | HPGDKMT2AMEN1KCNH2LMNA | |
| SCHEMBL7506840 | 0.84 | TOP2A (0.40) | HPGDKMT2AMEN1KCNH2LMNA | |
| SCHEMBL7499418 | 0.83 | ADRB2 (0.41) | HPGDKMT2AMEN1MAPTTHRB | |
| SCHEMBL7497474 | 0.82 | ADRB2 (0.40) | HPGDKMT2AMEN1MAPTTHRB | |
| SCHEMBL7492547 | 0.81 | KCNH2 (0.39) | HPGDKMT2AMEN1KCNH2LMNA | |
| SCHEMBL7498890 | 0.80 | ADRB2 (0.41) | HPGDKMT2AMEN1MAPTTHRB | |
| SCHEMBL7010280 | 0.80 | ADRB2 (0.42) | HPGDKMT2AMEN1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882725-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6025370-A | METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS | TOYAMA CHEMICAL CO., LTD. (JP) | 2000-02-15 | — | — | US | disclosed |
| EP-0882725-A1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |