Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000272 | 0.88 | KMT2A (0.42) | KMT2ARAB9AHPGDSMN1; SMN2MAPT | |
| SCHEMBL8853902 | 0.82 | RARB (0.43) | KMT2ARAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL8853910 | 0.82 | RARB (0.43) | KMT2ARAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL10000256 | 0.82 | RARB (0.43) | KMT2ARAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL9189096 | 0.77 | POLB (0.45) | KMT2AHPGDMAPTALDH1A1LMNA | |
| SCHEMBL9189100 | 0.77 | POLB (0.45) | KMT2AHPGDMAPTALDH1A1LMNA | |
| SCHEMBL9186042 | 0.77 | LSS (0.43) | KMT2AHPGDMAPTCYP19A1ALDH1A1 | |
| SCHEMBL9186038 | 0.77 | LSS (0.43) | KMT2AHPGDMAPTCYP19A1ALDH1A1 | |
| SCHEMBL8853553 | 0.77 | RARB (0.44) | KMT2ARAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL8853559 | 0.77 | RARB (0.44) | KMT2ARAB9ASMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541081-B1 | Compounds with only a side chain for use in liquid crystal mixtures | AVENTIS RES & TECH GMBH & CO (DE) | 2002-04-10 | — | — | EP | disclosed |