Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.88 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | KIF11 | P52732 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509578 | 0.94 | LOXL2 (1.00) | LOXL2CYP2A6TSHRHSD17B10HRH3 | |
| Hydrochloric Acid SCHEMBL8135282 | 0.91 | LOXL2 (0.95) | LOXL2CYP2A6TSHRHSD17B10CYP19A1 | |
| SCHEMBL13184538 | 0.84 | KDM4E (0.59) | LOXL2HRH3KDM4ECYP3A4MAPT | |
| SCHEMBL16848648 | 0.82 | LOXL2 (0.58) | LOXL2CYP2A6TSHRHSD17B10HRH3 | |
| SCHEMBL14155434 | 0.82 | LOXL2 (0.58) | LOXL2CYP2A6TSHRHSD17B10HRH3 | |
| SCHEMBL18664438 | 0.82 | LOXL2 (0.59) | LOXL2CYP2A6TSHRHSD17B10HRH3 | |
| SCHEMBL21786654 | 0.79 | LOXL2 (0.73) | LOXL2CYP2A6TSHRHSD17B10HRH3 | |
| SCHEMBL1983767 | 0.79 | LOXL2 (0.55) | LOXL2CYP2A6TSHRHSD17B10CYP19A1 | |
| SCHEMBL10243323 | 0.78 | CYP2A6 (0.86) | LOXL2CYP2A6TSHRHSD17B10HRH3 | |
| SCHEMBL4651866 | 0.78 | CYP2A6 (0.86) | LOXL2CYP2A6TSHRHSD17B10HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9977294-B2 | Liquid crystal display device | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) | 2018-05-22 | — | — | US | disclosed |
| US-8138209-B2 | Substituted picolinamides as MAO-B inhibitors useful for treating obesity | JENRIN DISCOVERY, INC. (US) | 2012-03-20 | — | — | US | disclosed |