Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3189969 | 0.93 | BBOX1 (0.45) | BBOX1LMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL9372219 | 0.82 | BBOX1 (0.59) | BBOX1LMNAMAPK1SLC22A6GABRR1 | |
| SCHEMBL6163047 | 0.77 | — | — | |
| SCHEMBL4557294 | 0.74 | BBOX1 (0.33) | BBOX1TERT | |
| SCHEMBL11048732 | 0.73 | BBOX1 (0.41) | BBOX1MAPK1TERTCYP1A2SMN1; SMN2 | |
| SCHEMBL9074301 | 0.72 | BBOX1 (0.37) | BBOX1 | |
| SCHEMBL7310546 | 0.70 | BBOX1 (0.35) | BBOX1TSHRFFAR3 | |
| SCHEMBL11315839 | 0.65 | — | — | |
| SCHEMBL1616368 | 0.64 | — | — | |
| Succinic Acid SCHEMBL27494088 | 0.63 | LMNA (0.75) | LMNAEGLN1ALKBH5SUCNR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597423-B1 | Azetidinone compound and process for preparation thereof | TANABE SEIYAKU CO (JP) | 2002-03-06 | — | — | EP | claimed |
| US-5847115-A | Azetidinone compound and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1998-12-08 | — | — | US | claimed |
| EP-0597423-A2 | Azetidinone compound and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-18 | — | — | EP | claimed |
| EP-0597423-B1 | Azetidinone compound and process for preparation thereof | TANABE SEIYAKU CO (JP) | 2002-03-06 | — | — | EP | disclosed |
| EP-0635488-B1 | Novel process for preparing azetidinone compound and novel starting compound therefor | TANABE SEIYAKU CO (JP) | 2001-09-26 | — | — | EP | disclosed |
| US-6011150-A | SYNTHETIC INTERMEDIATE OF A 1 BETA-METHYLCARBAPENEM DERIVATIVE | TANABE SEIYAKU CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| US-5847115-A | Azetidinone compound and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1998-12-08 | — | — | US | disclosed |
| US-5631363-A | ANTIBIOTIC INTERMEDIATE | TANABE SEIYAKU CO., LTD. (JP) | 1997-05-20 | — | — | US | disclosed |
| US-5550229-A | REACTING SPECIFIED ALKANAMIDE WITH SUBSTITUTED AZETIDINONE IN PRESENCE OF BASE | TANABE SEIYAKU CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| US-5442055-A | Chemical intermediates for carbapenicillins | TANABE SEIYAKU CO., LTD. (JP) | 1995-08-15 | — | — | US | disclosed |
| EP-0635488-A2 | Novel process for preparing azetidinone compound and novel starting compound therefor | TANABE SEIYAKU CO., LTD. (JP) | 1995-01-25 | — | — | EP | disclosed |
| EP-0597423-A2 | Azetidinone compound and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-18 | — | — | EP | disclosed |