Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | CCNC | P24863 | 3/20 | 0.55 |
| ▸ | CDK8 | P49336 | 3/20 | 0.55 |
| ▸ | HTR1A | P08908 | 4/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7504935 | 0.90 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1KDM4EHTTHSD17B10 | |
| SCHEMBL7502757 | 0.89 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1KDM4EHTTHSD17B10 | |
| SCHEMBL7507682 | 0.89 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1KDM4EHTTHSD17B10 | |
| SCHEMBL7503833 | 0.86 | CCNC (0.53) | SMN1; SMN2ALDH1A1KDM4EHTTHSD17B10 | |
| SCHEMBL7507742 | 0.86 | HTR1A (0.69) | SMN1; SMN2ALDH1A1KDM4EHTTHSD17B10 | |
| SCHEMBL7505881 | 0.86 | CCNC (0.53) | SMN1; SMN2ALDH1A1KDM4EHTTHSD17B10 | |
| SCHEMBL7508330 | 0.83 | TRPA1 (0.53) | SMN1; SMN2ALDH1A1KDM4EHTTHSD17B10 | |
| SCHEMBL7507415 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1KDM4EHTTHSD17B10 | |
| SCHEMBL7505350 | 0.82 | CCNC (0.71) | SMN1; SMN2ALDH1A1KDM4EHTTCCNC | |
| SCHEMBL7507351 | 0.82 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1KDM4EHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326331-B1 | Substituted quinolines and cinnolines | DOW AGROSCIENCES LLC (US) | 2002-04-17 | — | — | EP | disclosed |
| CN-1034204-C | Substituted quinolines and cinnolines | LILLY CO ELI (US) | 1997-03-12 | — | — | CN | disclosed |