Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CCNC | P24863 | 4/20 | 0.42 |
| ▸ | CDK8 | P49336 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23202861 | 0.86 | HTR1A (0.47) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL7505544 | 0.86 | HTR1A (0.54) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL7505881 | 0.86 | CCNC (0.53) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL30827848 | 0.86 | HTR1A (0.47) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL7510138 | 0.86 | HTR1A (0.49) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL7504497 | 0.84 | LMNA (0.56) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL7505000 | 0.84 | CCNC (0.53) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL7505428 | 0.84 | CCNC (0.53) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL7509062 | 0.83 | HTR1A (0.53) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL7501348 | 0.83 | CCNC (0.47) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326331-B1 | Substituted quinolines and cinnolines | DOW AGROSCIENCES LLC (US) | 2002-04-17 | — | — | EP | disclosed |
| CN-1034204-C | Substituted quinolines and cinnolines | LILLY CO ELI (US) | 1997-03-12 | — | — | CN | disclosed |
| US-5294622-A | Fungicides, insecticides, miticides | DOWELANCO (US) | 1994-03-15 | — | — | US | disclosed |
| US-5114939-A | Amine or ether substitutes compounds of quinoline or cinnoline | DOWELANCO (US) | 1992-05-19 | — | — | US | disclosed |
| CN-1034717-A | The quinoline and the cinnolines that replace | LILLY CO ELI (US) | 1989-08-16 | — | — | CN | disclosed |