Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 6/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7504921 | 0.95 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TSHRTDP1L3MBTL1 | |
| SCHEMBL5710554 | 0.84 | SCN1A (0.62) | ALDH1A1HSD17B10TSHRTDP1L3MBTL1 | |
| SCHEMBL26696240 | 0.83 | MAPT (0.51) | ALDH1A1HSD17B10TSHRTDP1L3MBTL1 | |
| SCHEMBL7497377 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRTDP1L3MBTL1 | |
| SCHEMBL25438784 | 0.80 | KMT2A (0.54) | ALDH1A1HSD17B10TSHRTDP1L3MBTL1 | |
| SCHEMBL15771473 | 0.78 | ALDH1A1 (0.64) | ALDH1A1HSD17B10TSHRTDP1L3MBTL1 | |
| SCHEMBL4040621 | 0.77 | ALDH1A1 (0.77) | ALDH1A1HSD17B10TSHRTDP1L3MBTL1 | |
| SCHEMBL975212 | 0.77 | TSHR (0.77) | ALDH1A1HSD17B10TSHRTDP1L3MBTL1 | |
| SCHEMBL31091519 | 0.76 | ALDH1A1 (0.66) | ALDH1A1HSD17B10TSHRTDP1L3MBTL1 | |
| SCHEMBL23748669 | 0.76 | TSHR (0.66) | ALDH1A1HSD17B10TSHRTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124788-A4 | BIS(HALOETHYL)AMINOBENZENE DERIVATIVES | SHIONOGI BIORES CORP (US) | 2002-11-06 | — | — | EP | claimed |
| EP-1124788-A2 | BIS(HALOETHYL)AMINOBENZENE DERIVATIVES | Shionogi Bioresearch Corporation (US) | 2001-08-22 | — | — | EP | claimed |
| WO-2000024361-A2 | BIS(HALOETHYL)AMINOBENZENE DERIVATIVES | SHIONOGI BIORESEARCH CORP. (US) | 2000-05-04 | — | — | WO | claimed |
| EP-1124788-A4 | BIS(HALOETHYL)AMINOBENZENE DERIVATIVES | SHIONOGI BIORES CORP (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-1250326-A2 | INDAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND THEIR USE FOR MEDIATING OR INHIBITING CELL PROLIFERATION | AGOURON PHARMACEUTICALS, INC. (US) | 2002-10-23 | — | — | EP | disclosed |
| EP-1124788-A2 | BIS(HALOETHYL)AMINOBENZENE DERIVATIVES | Shionogi Bioresearch Corporation (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2001053268-A2 | INDAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND THEIR USE FOR MEDIATING OR INHIBITING CELL PROLIFERATION | AGOURON PHARMACEUTICALS, INC. (US) | 2001-07-26 | — | — | WO | disclosed |
| WO-2000024361-A2 | BIS(HALOETHYL)AMINOBENZENE DERIVATIVES | SHIONOGI BIORESEARCH CORP. (US) | 2000-05-04 | — | — | WO | disclosed |