Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 16/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5121254 | 0.96 | PRKCI (0.62) | PRKCIKDM4EALDH1A1LMNAGAA | |
| SCHEMBL5809171 | 0.90 | PRKCI (0.48) | PRKCIADORA2AADORA1 | |
| SCHEMBL7172515 | 0.89 | ALDH1A1 (0.52) | PRKCIKDM4EALDH1A1LMNAGAA | |
| SCHEMBL5129890 | 0.88 | PRKCI (0.51) | PRKCIADORA2AADORA1 | |
| SCHEMBL5121765 | 0.86 | PRKCI (0.57) | PRKCIKDM4EALDH1A1LMNAGAA | |
| SCHEMBL5814772 | 0.85 | ADORA2A (0.48) | PRKCIKDM4EALDH1A1LMNAGAA | |
| SCHEMBL5126022 | 0.85 | CLK4 (0.54) | PRKCIKDM4EALDH1A1LMNAGAA | |
| SCHEMBL5809508 | 0.84 | GAA (0.40) | PRKCIKDM4EALDH1A1LMNAGAA | |
| SCHEMBL8180806 | 0.83 | FYN (0.46) | PRKCIKDM4EALDH1A1LMNAGAA | |
| SCHEMBL7175621 | 0.83 | GAA (0.47) | PRKCIKDM4EALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920431-A1 | THIENOPYRIMIDINES | MERCK PATENT GmbH (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998006722-A1 | THIENOPYRIMIDINES | MERCK PATENT GMBH (DE) | 1998-02-19 | — | — | WO | disclosed |