Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 5/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.42 |
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5733629 | 0.89 | ADRB2 (0.48) | ADRB2TDP1LMNASTAT3KMT2A | |
| SCHEMBL6783818 | 0.89 | ADRB2 (0.59) | ADRB2TDP1TOP2ATOP2BSTAT3 | |
| SCHEMBL7504273 | 0.87 | ADRB2 (0.47) | ADRB2TDP1LMNAKMT2AKCNH2 | |
| SCHEMBL7500713 | 0.86 | ADRB2 (0.47) | ADRB2TDP1LMNASTAT3KMT2A | |
| SCHEMBL7496082 | 0.86 | KCNH2 (0.48) | ADRB2TDP1LMNAKMT2AKCNH2 | |
| SCHEMBL7599453 | 0.85 | ADRB2 (0.65) | ADRB2LMNATOP2ATOP2BSTAT3 | |
| SCHEMBL2081998 | 0.85 | ADRB2 (0.45) | ADRB2TDP1LMNASTAT3KMT2A | |
| SCHEMBL9148042 | 0.84 | ADRB2 (0.55) | ADRB2TDP1TOP2ATOP2BSTAT3 | |
| SCHEMBL115123 | 0.83 | ADRB2 (0.54) | ADRB2TDP1TOP2ATOP2BSTAT3 | |
| SCHEMBL2844967 | 0.83 | ADRB2 (0.68) | ADRB2TOP2ATOP2BSTAT3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882725-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6025370-A | METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS | TOYAMA CHEMICAL CO., LTD. (JP) | 2000-02-15 | — | — | US | disclosed |
| EP-0882725-A1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |