Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 5/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.41 |
| ▸ | STAT3 | P40763 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6783818 | 0.91 | ADRB2 (0.59) | ADRB2TDP1KCNH2HTTKMT2A | |
| SCHEMBL115123 | 0.90 | ADRB2 (0.54) | ADRB2TDP1KCNH2HTTKMT2A | |
| SCHEMBL4466378 | 0.89 | ADRB2 (0.53) | ADRB2TDP1KCNH2HTTKMT2A | |
| SCHEMBL14387521 | 0.88 | KCNH2 (0.46) | ADRB2TDP1KCNH2TOP2ATOP2B | |
| SCHEMBL116273 | 0.88 | ADRB2 (0.52) | ADRB2TDP1KCNH2HTTKMT2A | |
| SCHEMBL8927420 | 0.87 | ADRB2 (0.51) | ADRB2TDP1KCNH2HTTKMT2A | |
| SCHEMBL2082379 | 0.87 | TDP1 (0.45) | ADRB2TDP1HTTKMT2ASTAT3 | |
| SCHEMBL2082380 | 0.87 | TDP1 (0.45) | ADRB2TDP1HTTKMT2ASTAT3 | |
| SCHEMBL5733629 | 0.86 | ADRB2 (0.48) | ADRB2TDP1KCNH2KMT2ASTAT3 | |
| SCHEMBL5733774 | 0.86 | ADRB2 (0.48) | ADRB2TDP1KCNH2KMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457104-A | Antibacterials | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | disclosed |