Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7496362 | 0.88 | POLB (0.55) | LMNAKDM4EL3MBTL1TP53MEN1 | |
| SCHEMBL7499083 | 0.82 | KDM4E (0.45) | LMNAKDM4EMEN1KMT2A | |
| SCHEMBL7506345 | 0.78 | GAA (0.57) | LMNAKDM4EL3MBTL1TP53MEN1 | |
| SCHEMBL7504683 | 0.78 | PDE4B (0.49) | LMNAKDM4EL3MBTL1KMT2ATSHR | |
| SCHEMBL7502793 | 0.74 | MAPT (0.58) | LMNAKDM4EL3MBTL1TP53MEN1 | |
| SCHEMBL7501749 | 0.74 | SQOR (0.53) | LMNAKDM4EL3MBTL1TP53MAPT | |
| SCHEMBL7502299 | 0.72 | KDM4E (0.62) | LMNAKDM4EL3MBTL1TP53MEN1 | |
| SCHEMBL7495437 | 0.71 | POLB (0.55) | TSHRPOLBCYP2C19 | |
| SCHEMBL7497628 | 0.70 | GAA (0.45) | LMNAKDM4EL3MBTL1TP53TSHR | |
| SCHEMBL7499764 | 0.70 | GAA (0.41) | LMNAKDM4EL3MBTL1TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826673-B1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5972946-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0826673-A1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |