Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495437 | 0.89 | POLB (0.55) | — | |
| SCHEMBL7507296 | 0.82 | LMNA (0.50) | KDM4ELMNAMEN1KMT2A | |
| SCHEMBL7495188 | 0.80 | POLB (0.54) | — | |
| SCHEMBL7501896 | 0.79 | L3MBTL1 (0.51) | KDM4EKMT2A | |
| SCHEMBL7496362 | 0.71 | POLB (0.55) | KDM4ELMNAMEN1KMT2A | |
| SCHEMBL7501517 | 0.70 | TP53 (0.52) | KMT2A | |
| SCHEMBL4805292 | 0.66 | PDE5A (0.51) | — | |
| SCHEMBL7504683 | 0.65 | PDE4B (0.49) | KDM4ELMNAKMT2A | |
| SCHEMBL2734020 | 0.65 | POLB (0.50) | KDM4ELMNAMEN1KMT2A | |
| SCHEMBL7500916 | 0.64 | POLB (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826673-B1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5972946-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0826673-A1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |