Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | AKT2 | P31751 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218191 | 0.88 | AKT1 (0.42) | AKT1AKT2CNR1NPC1RAB9A | |
| SCHEMBL6216979 | 0.84 | NR1H4 (0.54) | NR1H4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7507815 | 0.81 | AKT1 (0.42) | AKT1AKT2CNR1MEN1KMT2A | |
| SCHEMBL6219584 | 0.81 | AKT1 (0.43) | AKT1AKT2CNR1MEN1KMT2A | |
| SCHEMBL27571713 | 0.73 | SLC2A2 (0.48) | AKT1AKT2CNR1KMT2ANPC1 | |
| SCHEMBL7503171 | 0.72 | KDM4E (0.50) | AKT1AKT2CNR1MEN1KMT2A | |
| SCHEMBL6216161 | 0.71 | GABRA1 (0.52) | NR1H4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5250625 | 0.69 | GABRA1 (0.52) | NR1H4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7505252 | 0.68 | KDM4E (0.47) | AKT1AKT2MEN1KMT2ARAB9A | |
| SCHEMBL6215583 | 0.68 | GABRA1 (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259509-A1 | PROCESS FOR THE PREPARATION OF 6-METHYL-2-(4-METHYL-PHENYL)-IMIDAZO 1,2-A]PYRIMIDINE-3-(N,N-DIMETHYL-ACETAMIDE) AND INTERMEDIATES | EGIS GYOGYSZERGYAR RT. (HU) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001038327-A2 | PROCESS FOR THE PREPARATION OF 6-METHYL-2-(4-METHYL-PHENYL)-IMIDAZO[1,2-A]PYRIMIDINE-3-(N,N-DIMETHYL-ACETAMIDE) AND INTERMEDIATES | EGIS Gyógyszergyár Rt. (HU) | 2001-05-31 | — | — | WO | disclosed |