Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | AKT2 | P31751 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 11/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6219584 | 0.88 | AKT1 (0.43) | AKT1AKT2CNR1KDM4EHPGD | |
| SCHEMBL6218191 | 0.83 | AKT1 (0.42) | AKT1AKT2CNR1KDM4EHPGD | |
| SCHEMBL6216380 | 0.81 | KDM4E (0.50) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL7507802 | 0.81 | AKT1 (0.43) | AKT1AKT2CNR1MEN1KMT2A | |
| SCHEMBL7503171 | 0.74 | KDM4E (0.50) | AKT1AKT2CNR1KDM4EHPGD | |
| SCHEMBL6215583 | 0.69 | GABRA1 (0.69) | KDM4EHPGDHSD17B10LMNAALB | |
| SCHEMBL7505252 | 0.69 | KDM4E (0.47) | AKT1AKT2KDM4EHPGDHSD17B10 | |
| SCHEMBL6216568 | 0.69 | KDM4E (0.52) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL7507412 | 0.69 | ALDH1A1 (0.47) | AKT1AKT2CNR1KDM4EHPGD | |
| SCHEMBL6011806 | 0.66 | KDM4E (0.52) | KDM4EHPGDHSD17B10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259509-A1 | PROCESS FOR THE PREPARATION OF 6-METHYL-2-(4-METHYL-PHENYL)-IMIDAZO 1,2-A]PYRIMIDINE-3-(N,N-DIMETHYL-ACETAMIDE) AND INTERMEDIATES | EGIS GYOGYSZERGYAR RT. (HU) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001038327-A2 | PROCESS FOR THE PREPARATION OF 6-METHYL-2-(4-METHYL-PHENYL)-IMIDAZO[1,2-A]PYRIMIDINE-3-(N,N-DIMETHYL-ACETAMIDE) AND INTERMEDIATES | EGIS Gyógyszergyár Rt. (HU) | 2001-05-31 | — | — | WO | disclosed |