Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.62 |
| ▸ | NPC1 | O15118 | 10/20 | 0.62 |
| ▸ | GAA | P10253 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.59 |
| ▸ | MITF | O75030 | 2/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.59 |
| ▸ | KDM5A | P29375 | 1/20 | 0.59 |
| ▸ | KDM5C | P41229 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | APP | P05067 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13290937 | 0.89 | RAB9A (0.60) | RAB9AKDM4EALDH1A1NPC1GAA | |
| SCHEMBL13290931 | 0.88 | KDM4E (0.57) | RAB9AKDM4EALDH1A1NPC1GAA | |
| SCHEMBL13290926 | 0.86 | APP (0.72) | RAB9AKDM4EALDH1A1NPC1GAA | |
| SCHEMBL2538990 | 0.85 | RAB9A (0.72) | RAB9AKDM4EALDH1A1NPC1GAA | |
| SCHEMBL2536926 | 0.85 | APP (0.72) | RAB9AKDM4EALDH1A1NPC1GAA | |
| SCHEMBL22393194 | 0.81 | GRM5 (0.47) | RAB9AKDM4EALDH1A1NPC1GAA | |
| SCHEMBL22403253 | 0.78 | RAB9A (0.47) | RAB9AKDM4EALDH1A1NPC1GAA | |
| SCHEMBL17626882 | 0.77 | ALDH1A1 (1.00) | RAB9AKDM4EALDH1A1NPC1GAA | |
| SCHEMBL13290930 | 0.76 | APP (0.47) | RAB9AKDM4EALDH1A1NPC1GAA | |
| SCHEMBL22393188 | 0.75 | RAB9A (0.45) | RAB9AKDM4EALDH1A1NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100143251-A1 | COMPOUNDS AND AMYLOID PROBES THEREOF FOR THERAPEUTIC AND IMAGING USES | MOLECULAR NEUROIMAGING, LLC | 2010-06-10 | — | — | US | disclosed |
| EP-1259509-A1 | PROCESS FOR THE PREPARATION OF 6-METHYL-2-(4-METHYL-PHENYL)-IMIDAZO 1,2-A]PYRIMIDINE-3-(N,N-DIMETHYL-ACETAMIDE) AND INTERMEDIATES | EGIS GYOGYSZERGYAR RT. (HU) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001038327-A2 | PROCESS FOR THE PREPARATION OF 6-METHYL-2-(4-METHYL-PHENYL)-IMIDAZO[1,2-A]PYRIMIDINE-3-(N,N-DIMETHYL-ACETAMIDE) AND INTERMEDIATES | EGIS Gyógyszergyár Rt. (HU) | 2001-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100143251-A1 | COMPOUNDS AND AMYLOID PROBES THEREOF FOR THERAPEUTIC AND IMAGING USES | APP, BACE1, BACE2 | RAB9A 4657/4885KDM4E 4389/4885ALDH1A1 1882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.