SCHEMBL7508570

SCHEMBL7508570

O=[N+]([O-])c1ccc(C(/N=N/c2ccccc2)=N\Nc2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.60
GAA P10253 5/20 0.60
LMNA P02545 2/20 0.60
RAB9A P51151 6/20 0.60
NPC1 O15118 6/20 0.60
L3MBTL1 Q9Y468 4/20 0.60
KMT2A Q03164 10/20 0.58
MAPT P10636 9/20 0.58
MEN1 O00255 9/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
MAPK1 P28482 3/20 0.58
CASP3 P42574 1/20 0.58
SENP8 Q96LD8 1/20 0.58
SENP7 Q9BQF6 1/20 0.58
SENP6 Q9GZR1 1/20 0.58
HTT P42858 2/20 0.51
GFER P55789 1/20 0.47
NQO1 P15559 1/20 0.47
ALOX12 P18054 2/20 0.46
KDM4E B2RXH2 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7508574 1.00 ALDH1A1 (0.60) ALDH1A1GAALMNARAB9ANPC1
SCHEMBL11553982 0.95 RAB9A (0.64) ALDH1A1GAALMNARAB9ANPC1
SCHEMBL7510330 0.95 RAB9A (0.64) ALDH1A1GAALMNARAB9ANPC1
SCHEMBL11553978 0.95 RAB9A (0.64) ALDH1A1GAALMNARAB9ANPC1
SCHEMBL13929252 0.92 RAB9A (0.67) ALDH1A1GAALMNARAB9ANPC1
SCHEMBL3880145 0.87 RAB9A (0.60) ALDH1A1GAALMNARAB9ANPC1
SCHEMBL1674870 0.87 RAB9A (0.60) ALDH1A1GAALMNARAB9ANPC1
SCHEMBL3880149 0.87 RAB9A (0.60) ALDH1A1GAALMNARAB9ANPC1
SCHEMBL29371749 0.87 RAB9A (0.60) ALDH1A1GAALMNARAB9ANPC1
SCHEMBL13576443 0.85 NQO1 (0.48) ALDH1A1GAALMNARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6455210-B1 SUPPORT, PHOTOTHERMOGRAPHIC IMAGE- RECEIVING LAYERS, AND ANTIHALATION LAYER OR FILTER LAYERS OF A DYE AND A HEXAARYLBIIMIDAZOLE IN A DISPERSION OF A HYDROPHILIC POLYMER EASTMAN KODAK COMPANY 2002-09-24 US disclosed
US-20020106590-A1 AQUEOUS THERMALLY BEACHABLE COMPOSITION USEFUL IN A PHOTOTHERMOGRAPHIC ELEMENT CARESTREAM HEALTH, INC. 2002-08-08 US disclosed
EP-1217431-A2 An aqueous thermally bleachable composition useful in a photothermographic element EASTMAN KODAK COMPANY (US) 2002-06-26 EP disclosed
US-4201590-A Heat sensitive reactive products of hexaarylbiimidazole and antihalation dyes EASTMAN KODAK COMPANY (US) 1980-05-06 US disclosed
US-4196002-A HEXAARYLBISMIIDAZOLE, COLORLESS EASTMAN KODAK COMPANY (US) 1980-04-01 US disclosed