Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7502794 | 0.95 | SCN5A (0.37) | SCN5AKCNH2 | |
| SCHEMBL8575938 | 0.87 | SCN5A (0.42) | SCN5AKCNH2DPP4CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL7499392 | 0.86 | SCN5A (0.42) | SCN5AKCNH2DPP4CYP3A4CYP2D6 | |
| SCHEMBL7497788 | 0.83 | KCNH2 (0.35) | SCN5AKCNH2DPP4 | |
| SCHEMBL7498238 | 0.83 | KCNH2 (0.35) | SCN5AKCNH2DPP4 | |
| SCHEMBL7507090 | 0.83 | SCN5A (0.52) | SCN5AKCNH2CYP3A4 | |
| SCHEMBL7507361 | 0.83 | KCNH2 (0.35) | SCN5AKCNH2 | |
| SCHEMBL7506511 | 0.82 | KCNH2 (0.34) | SCN5AKCNH2CYP3A4 | |
| SCHEMBL7507186 | 0.82 | KDM4E (0.37) | SCN5AKCNH2 | |
| SCHEMBL7502899 | 0.81 | ALDH1A1 (0.40) | SCN5AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723545-B1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LAB (US) | 2002-05-08 | — | — | EP | claimed |