Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.38 |
| ▸ | DPP4 | P27487 | 7/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7499392 | 0.99 | SCN5A (0.42) | SCN5AKCNH2DPP4CYP3A4CYP2D6 | |
| SCHEMBL8570477 | 0.95 | SCN5A (0.45) | SCN5AKCNH2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7496978 | 0.94 | SCN5A (0.45) | SCN5AKCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL7508971 | 0.87 | SCN5A (0.34) | SCN5AKCNH2DPP4CYP3A4CYP2D6 | |
| SCHEMBL14515902 | 0.87 | SCN5A (0.40) | SCN5AKCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL8565903 | 0.86 | SCN5A (0.44) | SCN5AKCNH2KDM4EALDH1A1 | |
| SCHEMBL7927938 | 0.86 | SCN5A (0.44) | SCN5AKCNH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9055075 | 0.85 | SCN5A (0.43) | SCN5AKCNH2KDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8573819 | 0.85 | SCN5A (0.44) | SCN5AKCNH2KDM4EALDH1A1 | |
| SCHEMBL8563910 | 0.85 | SCN5A (0.44) | SCN5AKCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | claimed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | claimed |
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |