Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.46 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25855877 | 0.83 | FAAH (0.64) | RIPK1MAPT | |
| SCHEMBL19002577 | 0.81 | TBXAS1 (0.60) | TBXAS1TDP1L3MBTL1HRH1MAPT | |
| SCHEMBL607494 | 0.78 | TBXAS1 (1.00) | TBXAS1TDP1L3MBTL1HRH1MAPT | |
| SCHEMBL7443753 | 0.78 | TBXAS1 (1.00) | TBXAS1TDP1L3MBTL1HRH1MAPT | |
| SCHEMBL16116694 | 0.78 | TBXAS1 (1.00) | TBXAS1TDP1L3MBTL1HRH1MAPT | |
| SCHEMBL18248629 | 0.78 | TBXAS1 (0.77) | TBXAS1TDP1L3MBTL1HRH1MAPT | |
| SCHEMBL14959999 | 0.78 | TBXAS1 (0.77) | TBXAS1TDP1L3MBTL1HRH1MAPT | |
| SCHEMBL10772829 | 0.78 | TBXAS1 (0.77) | TBXAS1TDP1L3MBTL1HRH1MAPT | |
| SCHEMBL1009589 | 0.78 | TBXAS1 (1.00) | TBXAS1TDP1L3MBTL1HRH1MAPT | |
| Bicarbonate SCHEMBL9522433 | 0.77 | TBXAS1 (0.81) | TBXAS1TDP1L3MBTL1HRH1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001079177-A1 | CYCLIC DIAZA COMPOUNDS FOR TREATING NEURODEGENERATIVE DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2001-10-25 | — | — | WO | disclosed |