Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7510222 | 1.00 | POLB (0.40) | POLBTAS1R3TAS1R1TAS1R2PTGS1 | |
| SCHEMBL5505216 | 0.84 | POLB (0.37) | POLB | |
| SCHEMBL5505218 | 0.84 | POLB (0.37) | POLB | |
| SCHEMBL7511196 | 0.82 | POLB (0.32) | POLBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7511199 | 0.82 | POLB (0.32) | POLBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10508912 | 0.79 | CES2 (0.32) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10508908 | 0.79 | CES2 (0.32) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9689331 | 0.77 | CRBN (0.37) | POLB | |
| SCHEMBL9689334 | 0.77 | CRBN (0.37) | POLB | |
| SCHEMBL9589976 | 0.77 | HPGD (0.40) | PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823413-B1 | Intermediates for the preparation of benzoheterocyclic compounds | OTSUKA PHARMA CO LTD (JP) | 2002-02-13 | — | — | EP | claimed |