Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10508912 | 1.00 | CES2 (0.32) | CES2CES1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9377242 | 0.86 | — | — | |
| SCHEMBL9377247 | 0.86 | — | — | |
| SCHEMBL10774464 | 0.82 | ALDH1A1 (0.41) | — | |
| SCHEMBL9689331 | 0.79 | CRBN (0.37) | CES2CES1 | |
| SCHEMBL9689334 | 0.79 | CRBN (0.37) | CES2CES1 | |
| SCHEMBL7510222 | 0.79 | POLB (0.40) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7510218 | 0.79 | POLB (0.40) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL1345391 | 0.78 | CYP2D6 (0.38) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9562436 | 0.78 | CYP2D6 (0.38) | TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202763-B1 | 5,6-DIFLUORONAPHTHYRIDINES AND 5,6,8-TRIFLUORO-QUINOLINES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1989-11-08 | — | — | EP | disclosed |
| US-4657913-A | Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents | WARNER-LAMBERT COMPANY (US) | 1987-04-14 | — | — | US | disclosed |
| EP-0202763-A1 | 5,6-Difluoronaphthyridines and 5,6,8-trifluoro-quinolines as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1986-11-26 | — | — | EP | disclosed |