SCHEMBL7510568

SCHEMBL7510568

CCCC1CCC(c2ccc(C(=O)Oc3ccc(F)cc3)cc2)CC1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.59
MAPT P10636 4/20 0.56
ALDH1A1 P00352 3/20 0.56
LMNA P02545 1/20 0.56
KMT2A Q03164 5/20 0.50
MEN1 O00255 3/20 0.50
MAPK1 P28482 1/20 0.50
PARP10 Q53GL7 2/20 0.41
DGAT1 O75907 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ATM Q13315 1/20 0.39
HTR7 P34969 1/20 0.37
PARP14 Q460N5 1/20 0.37
PRSS1 P07477 1/20 0.37
ACR P10323 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8045326 1.00 CYP2C9 (0.59) CYP2C9MAPTALDH1A1LMNAKMT2A
SCHEMBL10806837 0.96 CYP2C9 (0.55) CYP2C9MAPTALDH1A1LMNAKMT2A
SCHEMBL10805073 0.96 CYP2C9 (0.55) CYP2C9MAPTALDH1A1LMNAKMT2A
SCHEMBL10806833 0.96 CYP2C9 (0.55) CYP2C9MAPTALDH1A1LMNAKMT2A
SCHEMBL11132104 0.96 CYP2C9 (0.55) CYP2C9MAPTALDH1A1LMNAKMT2A
SCHEMBL11131201 0.96 CYP2C9 (0.55) CYP2C9MAPTALDH1A1LMNAKMT2A
SCHEMBL10805071 0.96 CYP2C9 (0.55) CYP2C9MAPTALDH1A1LMNAKMT2A
SCHEMBL10938649 0.94 CYP2C9 (0.66) CYP2C9MAPTALDH1A1LMNAKMT2A
SCHEMBL10898816 0.94 CYP2C9 (0.66) CYP2C9MAPTALDH1A1LMNAKMT2A
SCHEMBL10655306 0.93 CYP2C9 (0.50) CYP2C9MAPTALDH1A1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8425988-B2 Polymerizable liquid crystal compound, polymerizable liquid crystal composition and anisotropic polymer JNC CORPORATION (JP) 2013-04-23 US disclosed
US-8425988-B2 Polymerizable liquid crystal compound, polymerizable liquid crystal composition and anisotropic polymer JNC CORPORATION (JP) 2013-04-23 US disclosed
US-8404316-B2 Polymerizable liquid crystal compound and its polymer JNC CORPORATION (JP) 2013-03-26 US disclosed
US-8404316-B2 Polymerizable liquid crystal compound and its polymer JNC CORPORATION (JP) 2013-03-26 US disclosed
US-8366962-B2 Polymerizable liquid crystal compounds having oxiranyl group, polymerizable liquid crystal compositions and polymers JNC CORPORATION (JP) 2013-02-05 US disclosed
US-8366962-B2 Polymerizable liquid crystal compounds having oxiranyl group, polymerizable liquid crystal compositions and polymers JNC CORPORATION (JP) 2013-02-05 US disclosed
US-20110147656-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUNDS HAVING OXIRANYL GROUP, POLYMERIZABLE LIQUID CRYSTAL COMPOSITIONS AND POLYMERS CHISSO CORPORATION (JP) 2011-06-23 US disclosed
US-20110147657-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND ANISOTROPIC POLYMER CHISSO CORPORATION (JP) 2011-06-23 US disclosed
US-20110086185-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND AND ITS POLYMER CHISSO CORPORATION (JP) 2011-04-14 US disclosed
US-7198827-B1 Nematic liquid crystal composition and liquid crystal display device using the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-04-03 US disclosed
EP-0742275-A1 LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME CHISSO CORPORATION (JP) 1996-11-13 EP disclosed
EP-0733692-A1 Liquid crystalline compound, liquid crystal composition containing the same, and display device Chisso Corporation (JP) 1996-09-25 EP disclosed
EP-0733610-A1 Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device Chisso Corporation (JP) 1996-09-25 EP disclosed
EP-0728829-A2 Liquid crystalline alkenylcyclohexene derivative, liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1996-08-28 EP disclosed
EP-0679707-A1 Liquid crystalline compound, liquid crystal composition and liquid crystal display element Chisso Corporation (JP) 1995-11-02 EP disclosed
EP-0672742-A1 A hexenediyne derivative and a liquid crystal composition CHISSO CORPORATION (JP) 1995-09-20 EP disclosed
EP-0640578-A1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition Chisso Corporation (JP) 1995-03-01 EP disclosed
EP-0306917-B1 A NEMATIC LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1992-06-17 EP disclosed
US-4917818-A STEEP VOLTAGE TRANSMITTANCE USED IN WATCHES, ELECTRONIC CALCULATORS CHISSO CORPORATION (JP) 1990-04-17 US disclosed
EP-0306917-A2 A nematic liquid crystal composition CHISSO CORPORATION (JP) 1989-03-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110086185-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND AND ITS POLYMER CCNT1, POF1B, CCND3 CYP2C9 1204/4885MAPT 2658/4885ALDH1A1 926/4885
US-20110147657-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND ANISOTROPIC POLYMER SSB, LEF1, UACA CYP2C9 2019/4885MAPT 12/4885ALDH1A1 2760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.