Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 18/20 | 0.56 |
| ▸ | MMP3 | P08254 | 11/20 | 0.56 |
| ▸ | MMP1 | P03956 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7504389 | 0.78 | MMP2 (0.76) | MMP2MMP3MMP1ALDH1A1HPGD | |
| SCHEMBL7501260 | 0.77 | MMP2 (0.64) | MMP2MMP3MMP1ALDH1A1HPGD | |
| SCHEMBL7509014 | 0.74 | MMP2 (0.73) | MMP2MMP3MMP1ALDH1A1HPGD | |
| SCHEMBL7504451 | 0.74 | MMP3 (0.77) | MMP2MMP3MMP1ALDH1A1HPGD | |
| SCHEMBL7504912 | 0.73 | MMP2 (0.61) | MMP2MMP3MMP1ALDH1A1HPGD | |
| SCHEMBL7507012 | 0.73 | MMP3 (0.71) | MMP2MMP3MMP1ALDH1A1HPGD | |
| SCHEMBL7499759 | 0.73 | MMP2 (0.67) | MMP2MMP3MMP1ALDH1A1HPGD | |
| SCHEMBL7502677 | 0.72 | MMP2 (1.00) | MMP2MMP3MMP1 | |
| SCHEMBL7443814 | 0.72 | MMP2 (1.00) | MMP2MMP3MMP1 | |
| SCHEMBL7443817 | 0.72 | MMP2 (1.00) | MMP2MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001930-B1 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LAB (US) | 2002-12-04 | — | — | EP | claimed |