Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 5/20 | 0.39 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.37 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381179 | 0.74 | PDE7A (0.43) | PDE7APDE7BGSTP1GSTM2MAPT | |
| SCHEMBL2968440 | 0.70 | PDE7A (0.68) | PDE7APDE7BGSTP1GSTM2MAPT | |
| SCHEMBL3772645 | 0.66 | PDE7A (0.49) | PDE7APDE7BGSTP1GSTM2MAPT | |
| SCHEMBL31222327 | 0.64 | L3MBTL1 (0.40) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5111726 | 0.64 | PDE7A (0.74) | PDE7APDE7BMAPTMEN1KMT2A | |
| SCHEMBL2947154 | 0.62 | MAPT (0.65) | MAPTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30847370 | 0.62 | L3MBTL1 (0.65) | MAPTGAAMEN1KMT2AHSP90AA1 | |
| SCHEMBL1165347 | 0.62 | L3MBTL1 (0.65) | MAPTGAAMEN1KMT2AHSP90AA1 | |
| SCHEMBL337857 | 0.62 | L3MBTL1 (0.68) | MAPTGAAMEN1KMT2AHSP90AA1 | |
| SCHEMBL18022797 | 0.62 | TDP1 (0.55) | MAPTGAAMEN1KMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910563-A1 | INTEGRIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0910563-A4 | — | — | 1999-04-28 | — | — | EP | disclosed |
| WO-1997001540-A1 | INTEGRIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-01-16 | — | — | WO | disclosed |