Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 7/20 | 0.43 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.43 |
| ▸ | DTYMK | P23919 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734150 | 0.80 | PDE7A (0.51) | PDE7APDE7BDTYMKHSP90AA1MEN1 | |
| SCHEMBL2968440 | 0.76 | PDE7A (0.68) | PDE7APDE7BMEN1KMT2APOLB | |
| SCHEMBL16225668 | 0.76 | GSTP1 (0.54) | PDE7APDE7BMEN1KMT2APOLB | |
| SCHEMBL27271638 | 0.75 | HSD17B10 (0.55) | PDE7APDE7BDTYMKHSP90AA1MEN1 | |
| SCHEMBL5111726 | 0.75 | PDE7A (0.74) | PDE7APDE7BMEN1KMT2APOLB | |
| SCHEMBL5423544 | 0.75 | PDE7A (0.42) | PDE7APDE7BMEN1KMT2APOLB | |
| SCHEMBL7510847 | 0.74 | PDE7A (0.39) | PDE7APDE7BHSP90AA1MEN1KMT2A | |
| SCHEMBL17985425 | 0.73 | PDE7A (0.55) | PDE7APDE7BMEN1KMT2APOLB | |
| SCHEMBL8989706 | 0.72 | PDE7A (0.51) | PDE7APDE7BHSP90AA1MEN1KMT2A | |
| SCHEMBL7643345 | 0.71 | GPR35 (0.47) | PDE7APDE7BHSP90AA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008213-A | A INHIBITOR OF VITRONECTIN RECEPTOR AND FIBRINOGEN RECEPTOR; USEFUL FOR INHIBITING PLATELET AGGREGATION AND OSTEOPOROSIS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-12-28 | — | — | US | disclosed |