Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | MARS1 | P56192 | 2/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL868480 | 0.77 | TDP1 (0.47) | AHRSRD5A2MARS1CRHR1HSD11B1 | |
| SCHEMBL6756395 | 0.74 | AHR (0.53) | AHRSRD5A2MARS1HSD11B1CNR1 | |
| SCHEMBL14785481 | 0.74 | IDO1 (0.39) | MAPK1CYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL15060592 | 0.73 | AHR (0.52) | AHRSRD5A2MARS1CRHR1HSD11B1 | |
| SCHEMBL3019241 | 0.72 | EDNRB (0.36) | AHRSRD5A2MARS1MAPK1TSHR | |
| SCHEMBL25964868 | 0.72 | AHR (0.40) | AHRSRD5A2MARS1CRHR1HSD11B1 | |
| SCHEMBL155790 | 0.71 | IDO1 (0.60) | MAPK1CYP1A2CYP2C9CYP2C19IDO1 | |
| SCHEMBL1137783 | 0.71 | IDO1 (0.60) | MAPK1CYP1A2CYP2C9CYP2C19IDO1 | |
| SCHEMBL20512348 | 0.70 | AHR (0.48) | AHRSRD5A2MARS1HSD11B1MAPK1 | |
| Ammonia Solution, Strong SCHEMBL1168618 | 0.69 | IDO1 (0.58) | MAPK1CYP1A2CYP2C9CYP2C19IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569301-B2 | 6, 6-dioxo-6-thia-1, 4-diaza-naphthalenes as herbicides | SYNGENTA LIMITED (GB) | 2013-10-29 | — | — | US | disclosed |
| US-8569301-B2 | 6, 6-dioxo-6-thia-1, 4-diaza-naphthalenes as herbicides | SYNGENTA LIMITED (GB) | 2013-10-29 | — | — | US | disclosed |
| US-8569301-B2 | 6, 6-dioxo-6-thia-1, 4-diaza-naphthalenes as herbicides | SYNGENTA LIMITED (GB) | 2013-10-29 | — | — | US | disclosed |
| EP-2430028-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2013-08-28 | — | — | EP | disclosed |
| EP-2430028-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2013-08-28 | — | — | EP | disclosed |
| US-20120115726-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
| US-20120115726-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
| US-20120115726-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
| EP-2430028-A1 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010130970-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010130970-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2010-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115726-A1 | HERBICIDAL COMPOUNDS | DDT, NAT1, DDAH1 | AHR 367/4885SRD5A2 917/4885MARS1 2704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.