Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKN1 | Q16512 | 1/20 | 0.55 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.55 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ESRRA | P11474 | 7/20 | 0.47 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511024 | 0.91 | TDP1 (0.47) | PKN1PKN2CHEK2TDP1ESRRA | |
| SCHEMBL7511020 | 0.91 | TDP1 (0.47) | PKN1PKN2CHEK2TDP1ESRRA | |
| SCHEMBL7521939 | 0.80 | PIM1 (0.60) | DGAT1SOAT1KCNH2CISD1PIM1 | |
| SCHEMBL7511829 | 0.80 | PIM1 (0.56) | PKN1PKN2TDP1CISD1NPC1 | |
| SCHEMBL7511827 | 0.80 | PIM1 (0.56) | PKN1PKN2TDP1CISD1NPC1 | |
| SCHEMBL7516143 | 0.80 | PIM1 (0.51) | TDP1CISD1PIK3CAPIK3CGPIK3CD | |
| SCHEMBL7511802 | 0.80 | PIM1 (0.51) | TDP1CISD1PIK3CAPIK3CGPIK3CD | |
| SCHEMBL7516825 | 0.80 | IGF1R (0.56) | TDP1CISD1PIK3CAPIK3CGPIK3CD | |
| SCHEMBL7511794 | 0.80 | PIM1 (0.51) | TDP1CISD1PIK3CAPIK3CGPIK3CD | |
| SCHEMBL7516149 | 0.80 | PIM1 (0.51) | TDP1CISD1PIK3CAPIK3CGPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6452014-B1 | THIAZOLIDINEDIONE COMPOUNDS | GERON CORPORATION | 2002-09-17 | — | — | US | disclosed |
| US-20020120144-A1 | Telomerase inhibitors and methods of their use | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-08-29 | — | — | US | disclosed |
| WO-2002051409-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORPORATION (US) | 2002-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020120144-A1 | Telomerase inhibitors and methods of their use | TERT, TERF2, POT1 | PKN1 3109/4885PKN2 3637/4885CHEK2 239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.