Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25863475 | 0.82 | PRKCA (0.38) | POLBHDAC6CA1CA2CA7 | |
| SCHEMBL7510072 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10POLBCA2 | |
| SCHEMBL24200402 | 0.78 | MEN1 (0.41) | ALDH1A1LMNAHSD17B10POLBFAAH | |
| SCHEMBL18412191 | 0.78 | HCAR2 (0.38) | LMNAPOLBHDAC6CA1CA2 | |
| SCHEMBL10641143 | 0.78 | — | — | |
| SCHEMBL17036695 | 0.76 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10CHRM5CHRM1 | |
| SCHEMBL4243347 | 0.75 | — | — | |
| SCHEMBL19449088 | 0.74 | MAPK1 (0.36) | POLBHDAC6CA1CA2CA7 | |
| SCHEMBL18272943 | 0.74 | TDP1 (0.47) | ALDH1A1LMNAHSD17B10CA1CA2 | |
| SCHEMBL18406307 | 0.74 | HCAR2 (0.48) | ALDH1A1LMNAPOLBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3459926-A1 | PHENYLATE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USES THEREOF | Institute of Materia Medica, Chinese Academy of Medical Sciences (CN) | 2019-03-27 | — | — | EP | disclosed |
| EP-0530515-B1 | Process for the preparation of N-halomethylpyrrole and intermediates | BASF AG (DE) | 2002-11-06 | — | — | EP | disclosed |
| EP-0530515-A1 | N-Alkanoylaminomethyl and N-Aroylaminomethyl pyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |
| US-5130328-A | Lima bean leaves | AMERICAN CYANAMID COMPANY (US) | 1992-07-14 | — | — | US | disclosed |