SCHEMBL7511083

SCHEMBL7511083

CCCCCCCCN1C(=O)NC2(CC(C)(C)N(O)C(C)(C)C2)C1=O

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 3/20 0.47
TACR1 P25103 1/20 0.47
PTGS1 P23219 3/20 0.41
PTGS2 P35354 3/20 0.41
MGLL Q99685 3/20 0.41
FAAH O00519 2/20 0.41
RAB9A P51151 2/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP19A1 P11511 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11091144 0.89 CNR1 (0.49) CNR1TACR1PTGS1PTGS2MGLL
SCHEMBL7699126 0.87 CNR1 (0.48) CNR1TACR1PTGS1PTGS2MGLL
SCHEMBL11488928 0.87 CNR1 (0.48) CNR1TACR1PTGS1PTGS2MGLL
SCHEMBL11484816 0.87 CNR1 (0.48) CNR1TACR1PTGS1PTGS2MGLL
SCHEMBL11490607 0.86 CNR1 (0.47) CNR1TACR1PTGS1PTGS2MGLL
SCHEMBL11476370 0.86 CNR1 (0.47) CNR1TACR1PTGS1PTGS2MGLL
SCHEMBL8523173 0.85 TACR1 (0.47) CNR1TACR1PTGS1PTGS2MGLL
SCHEMBL21679925 0.85 TACR1 (0.47) CNR1TACR1PTGS1PTGS2MGLL
SCHEMBL11479175 0.85 TACR1 (0.44) CNR1TACR1PTGS1PTGS2MGLL
SCHEMBL78208 0.85 TACR1 (0.47) CNR1TACR1PTGS1PTGS2MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5006577-A Durable, weatherproof CIBA-GEIGY CORPORATION (US) 1991-04-09 US claimed
EP-0309401-B2 Stabilization of coatings with N-hydroxy hindered amines CIBA SC HOLDING AG (CH) 2002-06-05 EP disclosed
EP-0309401-B1 Stabilization of coatings with N-hydroxy hindered amines CIBA GEIGY AG (CH) 1994-10-26 EP disclosed
US-5064883-A Stabilization of acid catalyzed thermoset resins with n-hydroxy hindered amines CIBA-GEIGY CORPORATION (US) 1991-11-12 US disclosed
US-5006577-A Durable, weatherproof CIBA-GEIGY CORPORATION (US) 1991-04-09 US disclosed
US-5004770-A Light, heat, and oxygen resistant CIBA-GEIGY CORPORATION (US) 1991-04-02 US disclosed