SCHEMBL8523173

SCHEMBL8523173

CCCCCCCCN1C(=O)NC2(CC(C)(C)N(C(C)=O)C(C)(C)C2)C1=O

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 1/20 0.47
CNR1 P21554 3/20 0.44
RAB9A P51151 1/20 0.41
PTGS1 P23219 3/20 0.39
PTGS2 P35354 3/20 0.39
MGLL Q99685 3/20 0.39
FAAH O00519 2/20 0.39
ALDH1A1 P00352 2/20 0.36
CYP1A2 P05177 3/20 0.35
CYP2C19 P33261 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
GAA P10253 1/20 0.35
MEN1 O00255 1/20 0.35
CYP2C9 P11712 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP19A1 P11511 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21679925 1.00 TACR1 (0.47) TACR1CNR1RAB9APTGS1PTGS2
SCHEMBL78208 1.00 TACR1 (0.47) TACR1CNR1RAB9APTGS1PTGS2
SCHEMBL6017697 0.91 TACR1 (0.45) TACR1CNR1RAB9AALDH1A1KMT2A
SCHEMBL4558186 0.88 TACR1 (0.39) TACR1CNR1RAB9APTGS1PTGS2
SCHEMBL11484911 0.86 TACR1 (0.44) TACR1CNR1RAB9APTGS1PTGS2
SCHEMBL7511083 0.85 CNR1 (0.47) TACR1CNR1RAB9APTGS1PTGS2
SCHEMBL11091144 0.85 CNR1 (0.49) TACR1CNR1PTGS1PTGS2MGLL
SCHEMBL11485859 0.84 TACR1 (0.47) TACR1CNR1RAB9APTGS1PTGS2
SCHEMBL11488928 0.84 CNR1 (0.48) TACR1CNR1RAB9APTGS1PTGS2
SCHEMBL11484816 0.84 CNR1 (0.48) TACR1CNR1RAB9APTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0931805-A1 TRIBLOCK OLIGOMERS, THERMOPLASTIC RESIN COMPOSITIONS, AND ANTIFOG MOLDINGS Mitsui Chemicals, Inc. (JP) 1999-07-28 EP disclosed
EP-0879855-A1 THERMOPLASTIC RESIN COMPOSITION AND FILM MADE FROM THE COMPOSITION Mitsui Chemicals, Inc. (JP) 1998-11-25 EP disclosed
US-4241208-A STABILIZERS OF SYNTHETIC POLYMERS AGAINST HEAT AND LIGHT SANKYO COMPANY LIMITED (JP) 1980-12-23 US disclosed
US-4066615-A PHOTOSTABILITY, THERMAL STABILITY SANKYO COMPANY LIMITED (JA) 1978-01-03 US disclosed