Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1014595 | 0.82 | TSHR (0.53) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL2496766 | 0.81 | TSHR (0.52) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL11075912 | 0.80 | ALDH1A1 (0.45) | TSHRALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL5406669 | 0.80 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL336349 | 0.80 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL7508195 | 0.79 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL2608176 | 0.79 | TSHR (0.69) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL712069 | 0.78 | — | — | |
| SCHEMBL705063 | 0.78 | — | — | |
| SCHEMBL229761 | 0.78 | TSHR (0.53) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753521-B1 | Process for distilling crude acrylic silane solution | CHISSO CORP (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-6307081-B1 | MACROMONOMER HAS ONE OR MORE SILICON-BONDED HYDROGEN ATOMS AT ONE MOLECULAR CHAIN TERMINAL, AND ONE OR MORE ALIPHATICALLY UNSATURATED SILICON-BONDED ORGANIC GROUPS AT THE OTHER MOLECULAR CHAIN TERMINAL. | DOW CORNING SILICONE COMPANY, LTD. (JP) | 2001-10-23 | — | — | US | disclosed |
| US-5824195-A | USING N-NITROSOPHENYLHYDROXYLAMINE SALT AND/OR COPPER DIALKYLDITHIOCARBAMATE SYNERGISTIC MIXTURE AS POLYMERIZATION INHIBITORS | CHISSO CORPORATION (JP) | 1998-10-20 | — | — | US | disclosed |
| EP-0753521-A2 | Process for distilling crude acrylic silane solution | Chisso Corporation (JP) | 1997-01-15 | — | — | EP | disclosed |