Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7503844 | 0.90 | MAPT (0.39) | ALDH1A1LMNAMAPTSMN1; SMN2TSHR | |
| SCHEMBL124198 | 0.87 | TP53 (0.40) | ALDH1A1LMNAMAPTSMN1; SMN2TSHR | |
| SCHEMBL7507796 | 0.86 | MAPT (0.39) | ALDH1A1MAPTSMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL7508048 | 0.84 | PTGS2 (0.40) | ALDH1A1KDM4EMAPTHSD17B10TP53 | |
| SCHEMBL7507094 | 0.84 | CETP (0.38) | ALDH1A1LMNAMAPTSMN1; SMN2TSHR | |
| SCHEMBL4442879 | 0.83 | HSD17B10 (0.38) | ALDH1A1MAPTSMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL4442467 | 0.83 | MAPT (0.38) | ALDH1A1LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL7514960 | 0.82 | MAPT (0.35) | ALDH1A1LMNAMAPTSMN1; SMN2TSHR | |
| SCHEMBL7507704 | 0.80 | CYP1A2 (0.38) | ALDH1A1LMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7509955 | 0.79 | PDGFRB (0.39) | MAPTPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206472-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AS NEUROTROPHIN PRODUCTION/SECRETION PROMOTING AGENT | Takeda Chemical Industries, Ltd. (JP) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001014372-A2 | OXAZOLE AND THIAZOLE DERIVATIVES AS NEUROTROPHIN PRODUCTION/SECRETION PROMOTING AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-03-01 | — | — | WO | disclosed |