Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CETP | P11597 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CEPT1 | Q9Y6K0 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124198 | 0.90 | TP53 (0.40) | MAPTSMN1; SMN2CETPLMNATSHR | |
| SCHEMBL15111130 | 0.86 | MAPT (0.37) | MAPTSMN1; SMN2LMNATSHRHTT | |
| SCHEMBL7503844 | 0.84 | MAPT (0.39) | MAPTSMN1; SMN2LMNATSHRHTT | |
| SCHEMBL7510444 | 0.83 | PTGS1 (0.34) | PTGS1EPHX2PTGS2RXRARXRB | |
| SCHEMBL7507704 | 0.83 | CYP1A2 (0.38) | MAPTSMN1; SMN2LMNATSHRHTT | |
| SCHEMBL7507094 | 0.83 | CETP (0.38) | MAPTSMN1; SMN2CETPLMNATSHR | |
| SCHEMBL7511214 | 0.82 | ALDH1A1 (0.39) | MAPTSMN1; SMN2LMNATSHRHTT | |
| SCHEMBL4442879 | 0.82 | HSD17B10 (0.38) | MAPTSMN1; SMN2TSHRHSD17B10TP53 | |
| SCHEMBL7502788 | 0.81 | GCGR (0.34) | MAPTLMNATP53FABP3 | |
| SCHEMBL7514365 | 0.80 | GCGR (0.35) | MAPTSMN1; SMN2TP53FABP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206472-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AS NEUROTROPHIN PRODUCTION/SECRETION PROMOTING AGENT | Takeda Chemical Industries, Ltd. (JP) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001014372-A2 | OXAZOLE AND THIAZOLE DERIVATIVES AS NEUROTROPHIN PRODUCTION/SECRETION PROMOTING AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-03-01 | — | — | WO | disclosed |