Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 18/20 | 0.74 |
| ▸ | NOS1 | P29475 | 18/20 | 0.64 |
| ▸ | NOS2 | P35228 | 14/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7510751 | 0.99 | NOS3 (0.72) | NOS3NOS1NOS2KCNH2 | |
| SCHEMBL7515413 | 0.94 | NOS3 (0.68) | NOS3NOS1NOS2KCNH2 | |
| SCHEMBL7817523 | 0.90 | NOS3 (0.76) | NOS3NOS1NOS2KCNH2 | |
| Hydrochloric Acid SCHEMBL7828295 | 0.89 | NOS3 (0.74) | NOS3NOS1NOS2KCNH2 | |
| SCHEMBL7824443 | 0.89 | NOS3 (0.73) | NOS3NOS1NOS2KCNH2 | |
| SCHEMBL7826140 | 0.88 | NOS3 (0.76) | NOS3NOS1NOS2KCNH2 | |
| Hydrochloric Acid SCHEMBL7832875 | 0.87 | NOS3 (0.74) | NOS3NOS1NOS2KCNH2 | |
| SCHEMBL7828344 | 0.85 | NOS3 (1.00) | NOS3NOS1NOS2KCNH2 | |
| SCHEMBL8191923 | 0.85 | NOS3 (0.68) | NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL7827939 | 0.84 | NOS3 (0.98) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861250-B1 | AMIDINE AND ISOTHIOUREA DERIVATIVES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2002-02-13 | — | — | EP | claimed |