Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 8/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.58 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27181000 | 0.92 | LMNA (0.82) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL30926878 | 0.92 | LMNA (0.82) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL30926713 | 0.91 | ALDH1A1 (0.71) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL27181115 | 0.91 | ALDH1A1 (0.71) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL27180166 | 0.85 | LMNA (0.62) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL30926869 | 0.85 | LMNA (0.62) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL15954334 | 0.83 | ALDH1A1 (0.80) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL17479201 | 0.82 | LMNA (0.67) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL15954150 | 0.82 | SIRT2 (0.66) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27181012 | 0.81 | LMNA (0.62) | LMNAALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | disclosed |