Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 6/20 | 0.35 |
| ▸ | FNTB | P49356 | 6/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7508656 | 0.90 | PGR (0.37) | FNTAFNTBNR3C1PGRNR3C2 | |
| SCHEMBL7516392 | 0.90 | KDR (0.36) | FNTAFNTBPGGT1BNR3C1PGR | |
| SCHEMBL7507024 | 0.88 | KDM1A (0.39) | FNTAFNTBPGGT1B | |
| SCHEMBL7503782 | 0.83 | KDR (0.41) | FNTAFNTBPGGT1B | |
| SCHEMBL7504857 | 0.83 | KDR (0.48) | NR3C1PGRNR3C2 | |
| SCHEMBL7511432 | 0.83 | KDM1A (0.44) | FNTAFNTBNR3C1PGRNR3C2 | |
| SCHEMBL7975983 | 0.79 | CCNT1 (0.36) | FNTAFNTB | |
| SCHEMBL7507970 | 0.78 | KDR (0.52) | FNTAFNTB | |
| SCHEMBL7994139 | 0.77 | KDR (0.41) | FNTAFNTBPGGT1B | |
| SCHEMBL7549609 | 0.73 | KDR (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147107-A4 | NOVEL ANGIOGENESIS INHIBITORS | MERCK & CO INC (US) | 2002-05-22 | — | — | EP | claimed |
| EP-1147107-A1 | NOVEL ANGIOGENESIS INHIBITORS | Merck & Co., Inc. (US) | 2001-10-24 | — | — | EP | claimed |
| WO-2000043393-A1 | NOVEL ANGIOGENESIS INHIBITORS | MERCK & CO., INC. (US) | 2000-07-27 | — | — | WO | claimed |
| EP-1147107-A4 | NOVEL ANGIOGENESIS INHIBITORS | MERCK & CO INC (US) | 2002-05-22 | — | — | EP | disclosed |
| EP-1147107-A1 | NOVEL ANGIOGENESIS INHIBITORS | Merck & Co., Inc. (US) | 2001-10-24 | — | — | EP | disclosed |
| US-6265403-B1 | TYROSINE INHIBITORS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |
| WO-2000043393-A1 | NOVEL ANGIOGENESIS INHIBITORS | MERCK & CO., INC. (US) | 2000-07-27 | — | — | WO | disclosed |