Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.36 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 2/20 | 0.33 |
| ▸ | FNTB | P49356 | 2/20 | 0.33 |
| ▸ | CCNK | O75909 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
| ▸ | KAT7 | O95251 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7503926 | 0.92 | CCNT1 (0.38) | CCNT1CCNE1CDK2CDK9CDK7 | |
| SCHEMBL7994416 | 0.91 | CCNT1 (0.37) | CCNT1CCNE1CDK2CDK9CDK7 | |
| SCHEMBL7505916 | 0.91 | CCNT1 (0.38) | CCNT1CCNE1CDK2CDK9CDK7 | |
| SCHEMBL7990463 | 0.89 | CHEK1 (0.39) | KDM1AFNTAFNTB | |
| SCHEMBL7991127 | 0.88 | CDK7 (0.46) | CCNT1CCNE1CDK2CDK9CDK7 | |
| SCHEMBL7993914 | 0.87 | HTR6 (0.38) | CCNT1CCNE1CDK2CDK9CDK7 | |
| SCHEMBL7986848 | 0.87 | CCNT1 (0.38) | CCNT1CCNE1CDK2CDK9CDK7 | |
| SCHEMBL7987305 | 0.86 | CCNT1 (0.42) | CCNT1CCNE1CDK2CDK9CDK7 | |
| SCHEMBL7993904 | 0.85 | KDR (0.38) | CDK2KDM1A | |
| SCHEMBL7990500 | 0.85 | KDM1A (0.41) | CCNT1CDK9KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265403-B1 | TYROSINE INHIBITORS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |