Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3795495 | 0.82 | OPRM1 (0.44) | LMNA | |
| SCHEMBL28522664 | 0.82 | OPRM1 (0.44) | LMNA | |
| SCHEMBL28693350 | 0.82 | OPRM1 (0.44) | LMNA | |
| SCHEMBL2851672 | 0.82 | OPRM1 (0.44) | LMNA | |
| SCHEMBL8210975 | 0.82 | OPRM1 (0.44) | LMNA | |
| SCHEMBL5959697 | 0.80 | TRPV1 (0.37) | LMNATRPV1 | |
| SCHEMBL3800947 | 0.79 | OPRM1 (0.46) | LMNA | |
| SCHEMBL7580335 | 0.76 | LMNA (0.67) | LMNATRPV1 | |
| SCHEMBL11723029 | 0.76 | LMNA (0.67) | LMNATRPV1 | |
| SCHEMBL21925059 | 0.76 | LMNA (0.67) | LMNATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812838-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVE SUBSTITUTED BY BICYCLIC AMINO GROUP, ESTER THEREOF, SALT THEREOF, AND BICYCLIC AMINE AS INTERMEDIATE THEREFOR | DAINIPPON PHARMACEUTICAL CO (JP) | 2002-05-02 | — | — | EP | disclosed |
| US-5990106-A | ANTIBIOTICS; 3-AZABICYCLO(3.2.0)HEPT-3-YL GROUP JOINED AT GIVEN POSITION OF A PYRIDONECARBOXYLIC ACID RESIDUE, SUCH AS 7-(1-AMINO-3-AZABICYCLO(3.2.0)HEPT-3-YL)-1-CYCLOPROPYL-6,8-DIFLUORO-1,4 -DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-11-23 | — | — | US | disclosed |
| US-5391571-A | Cholesterol ester hydrolase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-02-21 | — | — | US | disclosed |
| EP-0181136-B1 | OXINDOLE ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1992-03-25 | — | — | EP | disclosed |
| US-4686224-A | Oxindole antiinflammatory agents | PFIZER INC. (US) | 1987-08-11 | — | — | US | disclosed |
| US-4609650-A | ANTIANDROGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-09-02 | — | — | US | disclosed |