Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 8/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 8/20 | 0.48 |
| ▸ | PPID | Q08752 | 3/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.36 |
| ▸ | PPIB | P23284 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | PPIG | Q13427 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5368101 | 0.85 | ITGB1 (0.64) | ITGB1ITGA4 | |
| SCHEMBL5906839 | 0.79 | ITGB1 (0.52) | ITGB1ITGA4 | |
| SCHEMBL5906645 | 0.79 | ITGB1 (0.52) | ITGB1ITGA4 | |
| SCHEMBL5906642 | 0.79 | ITGB1 (0.52) | ITGB1ITGA4 | |
| SCHEMBL5906776 | 0.78 | ALOX5 (0.40) | ITGB1ITGA4 | |
| SCHEMBL2059146 | 0.77 | PPID (0.43) | PPIDELANECPB2PPIBPPIA | |
| SCHEMBL27646223 | 0.77 | FAAH (0.44) | JAK2JAK3TP53 | |
| SCHEMBL27646221 | 0.77 | FAAH (0.44) | JAK2JAK3TP53 | |
| SCHEMBL30142880 | 0.73 | PPID (0.53) | PPIDPPIBPPIAPPIGTACR1 | |
| SCHEMBL2059018 | 0.72 | ITGB1 (0.47) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002008206-A1 | 3-AMINO-2-(4-AMINOCARBONYLOXY)PHENYL-PROPIONIC ACID DERIVATIVES AS ALPHA-4- INTEGRIN INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-31 | — | — | WO | disclosed |