Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7512839 | 1.00 | FGF23 (0.47) | FGF23LMNAHPGDMAPTKCNN4 | |
| SCHEMBL406150 | 0.83 | FGF23 (0.53) | FGF23LMNAHPGDMAPTALDH1A1 | |
| SCHEMBL406151 | 0.83 | FGF23 (0.53) | FGF23LMNAHPGDMAPTALDH1A1 | |
| SCHEMBL2160910 | 0.83 | FGF23 (0.53) | FGF23LMNAHPGDMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL28411183 | 0.81 | FGF23 (0.52) | FGF23LMNAHPGDMAPTALDH1A1 | |
| SCHEMBL4889869 | 0.78 | CA12 (0.44) | FGF23LMNAHPGDKCNN4ALDH1A1 | |
| SCHEMBL4889877 | 0.78 | CA12 (0.44) | FGF23LMNAHPGDKCNN4ALDH1A1 | |
| SCHEMBL7068298 | 0.77 | FGF23 (0.57) | FGF23LMNAHPGDMAPTKCNN4 | |
| SCHEMBL28814470 | 0.75 | ALDH1A1 (0.42) | FGF23LMNAHPGDMAPTKCNN4 | |
| SCHEMBL2160707 | 0.75 | GRIN2D (0.59) | FGF23LMNAHPGDKCNN4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417400-B1 | O-(P-TOLYL)-BENZALDIMINE IS REACTED WITH HYDROXYLAMINE SALT TO FORM O-(P-TOLYL)-BENZALDOXIME; O-(P-TOLYL)-BENZONITRILE CHEMICAL INTERMEDIATES FOR DRUGS; OXIMINATION, IMINATION | SANOFI-SYNTHELABO (FR) | 2002-07-09 | — | — | US | disclosed |