Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | HPGD | P15428 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | TP53 | P04637 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | GALR3 | O60755 | 1/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514631 | 0.94 | KMT2A (0.75) | KMT2AMEN1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL7511572 | 0.92 | MEN1 (0.88) | KMT2AMEN1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL31504023 | 0.92 | MEN1 (0.88) | KMT2AMEN1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL3498895 | 0.88 | LMNA (0.78) | KMT2AMEN1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL13985697 | 0.86 | MAPK1 (0.84) | KMT2AMEN1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL14184554 | 0.86 | MEN1 (0.78) | KMT2AMEN1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL11888597 | 0.86 | NPC1 (0.76) | KMT2AMEN1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL15226896 | 0.85 | LMNA (0.65) | KMT2AMEN1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL31503975 | 0.84 | LMNA (0.78) | KMT2AMEN1MAPK1MAPTNPC1 | |
| SCHEMBL2956553 | 0.84 | HIF1A (0.93) | KMT2AMEN1MAPK1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020045548-A1 | Heat-sensitive recording sheet | SAITO CHEMICALS INSTITUTE CO., LTD. (JP) | 2002-04-18 | — | — | US | claimed |
| EP-1905762-A1 | PYRAZOLONE DERIVATIVE | Genecare Research Institute Co., Ltd (JP) | 2008-04-02 | — | — | EP | disclosed |
| EP-1900728-A1 | PHARMACEUTICAL COMPOSITION COMPRISING PYRAZOLONE DERIVATIVE | Genecare Research Institute Co., Ltd (JP) | 2008-03-19 | — | — | EP | disclosed |
| WO-2003007954-A2 | SULFONYL ARYL HYDROXAMATES AND THEIR USE AS MATRIX METALLOPROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2003-01-30 | — | — | WO | disclosed |
| US-20020045548-A1 | Heat-sensitive recording sheet | SAITO CHEMICALS INSTITUTE CO., LTD. (JP) | 2002-04-18 | — | — | US | disclosed |
| US-20020045548-A1 | Heat-sensitive recording sheet | SAITO CHEMICALS INSTITUTE CO., LTD. (JP) | 2002-04-18 | — | — | US | disclosed |