Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KDM6B | O15054 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7513136 | 1.00 | LMNA (0.53) | LMNAKDM6BMAPTTDP1MEN1 | |
| SCHEMBL13410533 | 0.85 | TDP1 (0.53) | LMNAMAPTTDP1MEN1KMT2A | |
| SCHEMBL7675848 | 0.84 | KDM6B (0.64) | LMNAKDM6BMAPTTDP1ALDH1A1 | |
| SCHEMBL7675842 | 0.84 | KDM6B (0.64) | LMNAKDM6BMAPTTDP1ALDH1A1 | |
| SCHEMBL13536803 | 0.82 | MAPT (0.55) | LMNAMAPTTDP1MEN1KMT2A | |
| SCHEMBL16431385 | 0.81 | KDM6B (0.64) | KDM6BTDP1ALOX15MAPK1 | |
| SCHEMBL4855639 | 0.78 | LMNA (0.58) | LMNAMAPTTDP1MEN1KMT2A | |
| SCHEMBL4855650 | 0.78 | LMNA (0.58) | LMNAMAPTTDP1MEN1KMT2A | |
| SCHEMBL10438568 | 0.78 | TSHR (0.54) | LMNAMAPTTDP1MEN1KMT2A | |
| SCHEMBL1857686 | 0.78 | LMNA (0.50) | LMNAKDM6BTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634408-B1 | DEPSIPEPTIDE DERIVATIVE, PRODUCTION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-5514773-A | PARASITICIDES, ANTHELMINTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-07 | — | — | US | disclosed |
| EP-0634408-A1 | DEPSIPEPTIDE DERIVATIVE, PRODUCTION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-01-18 | — | — | EP | disclosed |